About Ruth Roberts

Professor Ruth A Roberts, PhD, ATS, FBTS, ERT, FRSB, FRCPath. A co-founder of ApconiX, Ruth has 25 years of experience in leading roles in drug safety within large pharma. Ruth is also Chair and Director of Drug Discovery at The University of Birmingham, UK and was previously Global Head of Regulatory Safety at AstraZeneca. With over 140 publications in peer-reviewed journals, she is former president of the British Toxicology Society, former president of EUROTOX, former secretary to SOT and President of the Academy of Toxicological Sciences. Ruth was the recipient of the SOT Achievement award in 2002, the EUROTOX Bo Holmstedt Award in 2009 and the SOT Founders award in 2018 for outstanding leadership in toxicology. Ruth is an established science professional bringing rigorous expert thinking to toxicology, drug discovery and drug development.

Improve Drug Project Success by Understanding Drug Target Safety

Improve Drug Project Success by Understanding Drug Target Safety Join Professor Ruth Roberts, Director and Co-founder, ApconiX Ltd, Dr Claire Sadler, Project Toxicologist, ApconiX and Dr Leigh Ann Burns Nass, President/Owner, Magnolia Toxicology Consulting, LLC in a live webinar on Thursday, October 1, 2020 at 11am EDT (4pm BST/UK) In [...]

By |2022-09-21T14:19:36+01:00September 24th, 2020|Press|Comments Off on Improve Drug Project Success by Understanding Drug Target Safety

22nd Annual John Doull Symposium

22nd Annual John Doull Symposium Professor Ruth Roberts is guest speaker at the 22nd Annual John Doull Toxicology Symposium.  This event is taking place on the 29th of September at 9am CDT.  The Symposium is part of the University of Kansas, School of Medicine, Pharmacology, Toxicology & Therapeutics' series of [...]

By |2022-09-21T14:18:46+01:00September 17th, 2020|Events|Comments Off on 22nd Annual John Doull Symposium

Join Dr Richard Knight at the Digital AMR Conference

Join Dr Richard Knight at the Digital AMR Conference Join Dr Richard Knight, Co-founder and Director of ApconiX, Dr Peter Warn consultant at Magic Bullet Consulting, and Aleksander Danilovski, Chief Scientific Officer & Senior Vice President, Global R&D and Regulatory Affairs at Xelia at the 4th AMR Conference as [...]

By |2022-09-21T14:15:01+01:00August 19th, 2020|Events|Comments Off on Join Dr Richard Knight at the Digital AMR Conference

Science-Driven Design of the Preclinical Strategy: Case by Case

Science-Driven Design of the Preclinical Strategy: Case by Case Join Professor Ruth Roberts for the next science webinar in the Alderley Park Science Seminar Series: Science-Driven Design of the Preclinical Strategy: Case by Case Tuesday, 11 August 2020 12:00 pm to 1:00 pm Ruth will present lessons learned from >20 years’ [...]

By |2022-09-21T14:13:48+01:00August 5th, 2020|Events|Comments Off on Science-Driven Design of the Preclinical Strategy: Case by Case

Discover the Power of Target Safety Assessments in a SOT EHS Webinar

Discover the Power of Target Safety Assessments in a SOT EHS Webinar Professor Ruth Roberts, Dr Claire Sadler and Dr Leigh Ann Burns Nass present Target Safety Assessments: Knowledge is Power webinar in a SOT 2020 Exhibitor Hosted Session.  Membership of SOT is not required.  Registration for the webinar [...]

By |2022-09-21T14:12:41+01:00July 2nd, 2020|Events|Comments Off on Discover the Power of Target Safety Assessments in a SOT EHS Webinar

ApconiX Co-organises British Toxicology Society Meeting

ApconiX Co-organises British Toxicology Society Meeting The meeting that ApconiX is co-organising the British Toxicology Society  “Science-led Strategies for Success in Discovery and Development Toxicology” is being rearranged for a date later in 2020 - watch this space for updates! Sponsored by Lonza and AstraZeneca and co-organised by ApconiX, [...]

By |2022-09-21T14:08:28+01:00March 8th, 2020|Events|Comments Off on ApconiX Co-organises British Toxicology Society Meeting

Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity

Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity Abstract: Drug-induced liver injury (DILI) is of significant concern to drug development and regulatory review because of the limited success with existing preclinical models. For developing alternative methods, a large drug list is needed [...]

By |2021-08-12T15:22:56+01:00January 16th, 2020|Publications|Comments Off on Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity

Merry Christmas and a Happy New Year

Merry Christmas and a Happy New Year Team ApconiX had a fabulous time at their Christmas party - secret Santa brought tears of laughter and sorrow and the odd gasp!  A few team members went incognito. Wishing everyone a lovely holiday and the very best for the coming year.  [...]

By |2021-08-12T15:27:28+01:00December 19th, 2019|Events|Comments Off on Merry Christmas and a Happy New Year

Professor Ruth Roberts is Speaking at the American Association of Pharmaceutical Scientists

Professor Ruth Roberts is Speaking at the American Association of Pharmaceutical Scientists Professor Ruth Roberts, Co-Founder and Director of ApconiX will be speaking at the American Association of Pharmaceutical Scientists (AAPS) on Monday 4th November at 9:00am in a session entitled "Next Generation Technologies in Preclinical Development” chaired by Dr Shraddha [...]

By |2021-08-13T13:25:44+01:00October 30th, 2019|Events|Comments Off on Professor Ruth Roberts is Speaking at the American Association of Pharmaceutical Scientists

Acuity Target Safety Assessments: Knowledge is Power

Acuity Target Safety Assessments: Knowledge is Power A thorough understanding of potential target-related effects is crucial to making the right choices in drug discovery.  Experienced project toxicologists extract and interpret data from mouse knockouts, human gene mutations and known effects of modulators to determine the potential consequences of target inhibition or [...]

By |2021-08-13T13:28:13+01:00October 1st, 2019|Target Safety Assessments|Comments Off on Acuity Target Safety Assessments: Knowledge is Power
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