Study monitoring – What is it and why is it important to drug discovery projects? Guy Healing, Senior Toxicologist at ApconiX is interviewed by Jon Clements of Metamorphic PR Pharma companies need to ensure their drugs are safe but also that they work. In drug development, this requires numerous studies to [...]
Differential expression of cyclin-dependent kinases in the adult human retina in relation to CDK inhibitor retinotoxicity Abstract Cyclin-dependent kinases (CDKs) are a family of kinases associated predominantly with cell cycle control, making CDK inhibitors interesting candidates for anti-cancer therapeutics. However, retinal toxicity (loss of photoreceptors) has been associated with [...]
