ApconiX Ion Channels archive

We’re Celebrating the Connection Between hERG and Whiskey at SOT

Celebrating the Connection Between hERG and Whiskey Come and help us celebrate the connection between hERG and whiskey at our Booth #2028.  We’ll be at the 61st Society of Toxicology Annual Meeting and ToxExpo between 27th and 31st of March, 2022, in San Diego, California. hERG and Whiskey We’ll [...]

By |2023-09-28T15:16:57+01:00February 24th, 2022|Company News, Ion Channels|Comments Off on We’re Celebrating the Connection Between hERG and Whiskey at SOT

ApconiX Welcomes Hannah Jennings

ApconiX Welcomes Hannah Jennings ApconiX is delighted to welcome Hannah Jennings for a years’ Internship, joining the team working in our ion channel laboratory. Hannah graduated from the University of Liverpool with a degree in Biochemistry before studying for a MSc in Advanced Biological Sciences where she investigated the use [...]

By |2022-08-17T09:54:49+01:00November 24th, 2021|Ion Channels|Comments Off on ApconiX Welcomes Hannah Jennings

ApconiX Welcomes Dr Kevin Cunningham

ApconiX Welcomes Dr Kevin Cunningham ApconiX is delighted to welcome Dr Kevin Cunningham, who joins us until Christmas and will be working in our ion channel laboratory. Kevin graduated from Kingston University with a degree in Pharmacology before studying for a MSc in Cancer Biology at the University of [...]

By |2021-11-30T12:24:01+00:00November 18th, 2021|Ion Channels|Comments Off on ApconiX Welcomes Dr Kevin Cunningham

ApconiX Upgrade to a QPatch ll 48 Automated Patch Clamp to Meet Demand

ApconiX Upgrade to a QPatch ll 48 Automated Patch Clamp to Meet Demand ApconiX, the integrated toxicology and ion channel company, has acquired a QPatch ll 48 with temperature control to meet the increasing demand from their clients. As the first CRO to invest in QPatch II in the [...]

By |2021-08-20T12:04:07+01:00August 4th, 2021|Ion Channels|Comments Off on ApconiX Upgrade to a QPatch ll 48 Automated Patch Clamp to Meet Demand

ApconiX Is Recruiting an Expert Electrophysiologist

ApconiX Is Recruiting an Expert Electrophysiologist ApconiX is a team of world-renowned nonclinical safety experts with over 400 years of drug discovery and development expertise. We were formed in 2015 by three scientists with the drive and ambition to create a world-renowned company.  We are now looking to grow our [...]

By |2022-02-02T09:44:47+00:00July 7th, 2021|Ion Channels, Careers|Comments Off on ApconiX Is Recruiting an Expert Electrophysiologist

Cardiac Safety in Drug Development: CiPA

Cardiac Safety in Drug Development: CiPA In the second of a three-part series looking at cardiac safety testing in early drug discovery, Dr Michael Morton of ApconiX considers the CiPA initiative and how its integrated approach sits alongside existing strategies. What is the CiPA initiative and what does it [...]

By |2024-10-14T17:07:53+01:00February 19th, 2020|Ion Channels|Comments Off on Cardiac Safety in Drug Development: CiPA

My Brush with Greatness

My Brush with Greatness It is wonderful to see the original publication of patch-clamp methodology included in Nature’s 10 extraordinary papers (published 22 October 2019). The ground-breaking work of Neher and Sakmann sits alongside the discovery of the structure of DNA, cell reprogramming and birth of nanomaterials. At this [...]

By |2022-05-12T14:03:05+01:00January 16th, 2020|Ion Channels|Comments Off on My Brush with Greatness

An Ascorbate-Induced Increase in Sodium Current

An Ascorbate-Induced Increase in Sodium Current The Challenge It is not uncommon for our clients to synthesise compounds for testing in in vitro assays that are largely insoluble, and sometimes this requires consideration of novel vehicles.  Recently, when provided with a DMSO-insoluble compound, we explored using the aqueous solvent, [...]

By |2021-08-12T15:24:17+01:00January 16th, 2020|Ion Channels|Comments Off on An Ascorbate-Induced Increase in Sodium Current

Innovative Models for In Vitro Detection of Seizure

Innovative Models for In Vitro Detection of Seizure ApconiX is delighted that Dr Kim Rockley's article ‘ Innovative models for in vitro detection of seizure‘ has now been accepted for publication in Toxicology Research. The article highlights how new technologies such as microelectrode array and ion channel screening offer [...]

By |2022-08-17T09:59:32+01:00November 20th, 2019|Publications, Ion Channels|Comments Off on Innovative Models for In Vitro Detection of Seizure
Go to Top