ApconiX Ion Channels archive
ApconiX Welcomes Bethan Kelly ApconiX is delighted to welcome Bethan Kelly who joins for a years’ placement having just completed her second year of a bachelor’s degree in biology. Bethan becomes part of the ion channel laboratory team and will be working with Dr Michael Morton. Studying Biology Bethan [...]
Celebrating the Link Between hERG and Whiskey Come and help us celebrate the link between hERG and whiskey at our Booth #A6. We’ll be at the ELRIG Drug Discovery 2022 on the 4th and 5th of October, 2022, in London, UK. hERG and Whiskey We’ll be giving away ApconiX [...]
Celebrating the Connection Between hERG and Whiskey Come and help us celebrate the connection between hERG and whiskey at our Booth #2028. We’ll be at the 61st Society of Toxicology Annual Meeting and ToxExpo between 27th and 31st of March, 2022, in San Diego, California. hERG and Whiskey We’ll [...]
ApconiX Welcomes Hannah Jennings ApconiX is delighted to welcome Hannah Jennings for a years’ Internship, joining the team working in our ion channel laboratory. Hannah graduated from the University of Liverpool with a degree in Biochemistry before studying for a MSc in Advanced Biological Sciences where she investigated the use [...]
ApconiX Welcomes Dr Kevin Cunningham ApconiX is delighted to welcome Dr Kevin Cunningham, who joins us until Christmas and will be working in our ion channel laboratory. Kevin graduated from Kingston University with a degree in Pharmacology before studying for a MSc in Cancer Biology at the University of [...]
ApconiX Upgrade to a QPatch ll 48 Automated Patch Clamp to Meet Demand ApconiX, the integrated toxicology and ion channel company, has acquired a QPatch ll 48 with temperature control to meet the increasing demand from their clients. As the first CRO to invest in QPatch II in the [...]
ApconiX Is Recruiting an Expert Electrophysiologist ApconiX is a team of world-renowned nonclinical safety experts with over 400 years of drug discovery and development expertise. We were formed in 2015 by three scientists with the drive and ambition to create a world-renowned company. We are now looking to grow our [...]
Cardiac Safety in Drug Development: CiPA In the second of a three-part series looking at cardiac safety testing in early drug discovery, Dr Michael Morton of ApconiX considers the CiPA initiative and how its integrated approach sits alongside existing strategies. What is the CiPA initiative and what does it [...]
My Brush with Greatness It is wonderful to see the original publication of patch-clamp methodology included in Nature’s 10 extraordinary papers (published 22 October 2019). The ground-breaking work of Neher and Sakmann sits alongside the discovery of the structure of DNA, cell reprogramming and birth of nanomaterials. At this [...]
An Ascorbate-Induced Increase in Sodium Current The Challenge It is not uncommon for our clients to synthesise compounds for testing in in vitro assays that are largely insoluble, and sometimes this requires consideration of novel vehicles. Recently, when provided with a DMSO-insoluble compound, we explored using the aqueous solvent, [...]
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