ApconiX Ion Channels archive

Dr Michael Morton Is Presenting at 10th Nanion Annual User Meeting

Dr Michael Morton Is Presenting at 10th Nanion Annual User Meeting Dr Michael Morton, Director and Co-Founder will be speaking at the 10th  Nanion User Meeting on Thursday 17th of October, "Two Years of Experience and Learning with Patchliner".  The User Meeting is being held from Wednesday 17th to Thursday 18th [...]

By |2021-08-13T13:27:47+01:00October 13th, 2019|Ion Channels, Events|Comments Off on Dr Michael Morton Is Presenting at 10th Nanion Annual User Meeting

ApconiX Conduct Pilot Study with Axion Biosystems

ApconiX Conduct Pilot Study with Axion Biosystems We were thrilled to welcome Jayne Ingram from Axion Biosystems into the ApconiX laboratory to conduct a pilot study using their Maestro Pro microelectrode array (MEA) system and Ncardia iPSC-derived neuronal cells.  The cells were cultured for three weeks before Jayne arrived [...]

By |2021-09-08T16:57:57+01:00October 10th, 2019|Ion Channels, Toxicology|Comments Off on ApconiX Conduct Pilot Study with Axion Biosystems

ApconiX Are in Boston, USA at the End of August

ApconiX Are in Boston, USA at the End of August Dr Richard Knight and Professor Ruth Roberts are travelling to Boston at the end of August to meet with old colleagues and new contacts, promoting the company’s services in Project Toxicology, Ion Channel Screening and Assay Development, Target Safety [...]

By |2022-07-13T14:59:25+01:00August 20th, 2019|Events, Ion Channels, Target Safety Assessments, Toxicology|Comments Off on ApconiX Are in Boston, USA at the End of August

The Reductionist Approach

The Reductionist Approach The hERG assay has been a mainstay of safety screening in drug discovery for the last 2 decades. Aided by the development of high throughput automated technology, this important assay has brought unparalleled progress in our ability to design safer drugs without those properties that may lead to [...]

By |2021-08-13T13:44:03+01:00July 11th, 2019|Ion Channels|Comments Off on The Reductionist Approach

ApconiX Welcomes Priscilla Dumenu

ApconiX Welcomes Priscilla Dumenu ApconiX is delighted to welcome Priscilla Dumenu for a 2-week placement.  Priscilla will be working alongside Dr Michael Morton and Dr Karen Jones in the Ion Channel laboratory. Priscilla has just finished her second year studying Pharmacy at the University of Manchester.  The 5-year integrated master’s degree [...]

By |2021-08-13T13:46:56+01:00June 28th, 2019|Careers, Ion Channels|Comments Off on ApconiX Welcomes Priscilla Dumenu

Sophion’s Ion Channel Modulation Symposium

Sophion’s Ion Channel Modulation Symposium Dr Michael Morton will be attending Sophion’s Ion Channel Modulation Symposium, on the 19th to 20th of June 2019, at Clare College in Cambridge, UK. Sophion was founded almost twenty years ago by a group of passionate electrophysiologists and offers the some of the [...]

By |2024-02-19T10:38:32+00:00June 12th, 2019|Events, Ion Channels|Comments Off on Sophion’s Ion Channel Modulation Symposium

ApconiX Joins the MDC’s Virtual R&D platform

ApconiX Joins the MDC’s Virtual R&D platform ApconiX has joined the Medicines Discovery Catapult’s Virtual R&D platform.  This is a unique national network of consultants, private sector CROs, expert labs and public sector centres of excellence, providing medicines discovery expertise, services and virtual programme management. ApconiX specialises in ion [...]

By |2022-02-22T12:48:05+00:00June 6th, 2019|Ion Channels|Comments Off on ApconiX Joins the MDC’s Virtual R&D platform

ApconiX Welcomes Sushma Pabbineedi.

ApconiX Welcomes Sushma Pabbineedi. ApconiX is delighted to welcome Sushma Pabbineedi for a placement during May.  Sushma will be working alongside Dr Michael Morton and Dr Karen Jones in the ion channel laboratory. Sushma studied Biomedical Sciences and gained a bachelor’s degree from Manchester Metropolitan University.  She took a [...]

By |2022-02-22T12:55:17+00:00May 9th, 2019|Ion Channels, Careers|Comments Off on ApconiX Welcomes Sushma Pabbineedi.

Identification of Selective Inhibitors of The Epithelial Sodium Channel ?.

Identification of Selective Inhibitors of The Epithelial Sodium Channel ?. Victoria Miller, a PhD student from the Drug Discovery Centre at the University of Sussex recently spent a few months working in the ApconiX ion channel laboratory as a part of her research. Her PhD project titled “Identification of [...]

By |2022-02-22T13:01:37+00:00May 1st, 2019|Ion Channels, Events|Comments Off on Identification of Selective Inhibitors of The Epithelial Sodium Channel ?.

K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall

K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall Dr Michael Morton co-authored a paper recently published in the Journal of Cardiovascular Electrophysiology. The paper should serve as a reminder that ion channels which may not be the focus of regulatory guidance or [...]

By |2022-02-22T13:07:39+00:00April 18th, 2019|Ion Channels, Publications|Comments Off on K2p3.1 protein is expressed as a transmural gradient across the rat left ventricular free wall
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