Toxicology and DMPK Consultancy

Early consideration of potential safety liabilities is an important part of every drug discovery project. With our extensive and diverse experience of discovery and development, we have the expertise to design high quality, cost effective nonclinical safety packages that perfectly align with your project.

Working flexibly with discovery and development teams, our scientists help identify the key safety questions needed to deliver derisked compounds into clinical trials and through clinical development. We can design the overall safety strategy, deliver the toxicology /DMPK studies, author regulatory documents and support regulatory agency interactions.

The Right Nonclinical Choices Can Make the Difference Between Clinical Success and Failure

Drug Project Toxicology | ApconiX

Asking the right questions at the right time to make drugs safer and more effective

DMPK Project Support | ApconiX

Helping to understand and optimise drug metabolism and pharmacokinetics

toxicology specialists 1 scaled 1 | ApconiX

World leading toxicology expertise

Nonclinical Study Monitoring | ApconiX

The right professionals to ensure the right outcome

Project Management | ApconiX

Strategic planning and organisation to enable successful programme execution

Due Diligence | ApconiX

The right professionals to help quantify risk

inhilation | ApconiX

Ensuring the safety of novel inhaled therapies

Genetic Toxicology | ApconiX

Expert guidance on assessing effects on DNA mutations and chromosomal damage

Reproductive | ApconiX

Delivering the right data to support the inclusion of women and children in clinical trials

Safety Pharmacology | ApconiX

Assessing the impact of adverse effects on key organ systems. Evaluating the potential impact of off target pharmacological activity

Immunotoxicology | ApconiX

Assessing the role of the immune system in drug toxicity

Medical Devices | ApconiX

Expert toxicology and regulatory guidance

OELs and PDEs | ApconiX

Bespoke assessments by an expert toxicologist

video1 | ApconiX

Bespoke assessments by an expert toxicologist